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International Journal of Clinical & Medical Images

ISSN: 2376-0249

Clinical Image - International Journal of Clinical & Medical Images (2014) Volume 1, Issue 5

Ultra Structural Demonstration Of The Presence Of Dendritic Cells In Atherosclerotic Lesions Of The Aorta Of Rabbits With Experimental Hypercholesterolemia

Ultra Structural Demonstration Of The Presence Of Dendritic Cells In Atherosclerotic Lesions Of The Aorta Of Rabbits With Experimental Hypercholesterolemia

Author(s): Yuri V Bobryshev

The presence of dendritic cells in human atherosclerotic lesions and in atherosclerotic lesions in some animal models of atherosclerosis is well established [1]. However, whether dendritic cells do populate atherosclerotic lesions of rabbits with experimental hypercholesterolemia is still unknown. The micrographs included in the image show cells with typical ultrastructural features of dendritic cells [2]. The micrographs were obtained from sections of aortas of rabbits kept on cholesterol diet [3]. (Panel A): Semithin section of atherosclerotic lesion showing the area from which ultrastructural pictures were obtained; Section was stained with toluidine blue. (Panels B-D): Dendritic cells (marked by stars) containing cisterns of the tubulovesicular system (shown by arrows). Transmission Electron Microscopy (TEM). Ultrathin sections were stained with lead citrate and uranyl acetate.

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